PLANT CELL BIOTECHNOLOGY AND MOLECULAR BIOLOGY

Stress biology in agriculture encompasses the diverse physiological, biochemical, and molecular responses of plants to environmental challenges that directly influence crop productivity and food security. Both abiotic (non-living) stressors such as drought, salinity, and temperature extremes and biotic (living) stressors, including pests, pathogens, and weeds, cause significant yield losses while disrupting plant growth and metabolism. Their impacts are often compounded, as one stress can intensify vulnerability to another; for example, drought frequently increases susceptibility to pest attacks, reflecting the complexity of plant stress responses. Research in this field has revealed a wide array of tolerance mechanisms, ranging from genetic and epigenetic regulation to intricate signalling pathways that coordinate stress perception and adaptation. Advances in molecular breeding and biotechnology have accelerated the development of stress-resilient crops, with tools such as Marker-Assisted Selection (MAS), Quantitative Trait Loci (QTL) mapping, and genomic selection already applied successfully in maize, sorghum, and cotton. These approaches demonstrate the potential of integrating genomic insights with conventional breeding to strengthen crop resilience. Sustainable practices further complement genetic innovations, with strategies such as integrated pest management (IPM), precision agriculture, and the application of beneficial microorganisms offering ecologically sound alternatives to heavy chemical use. By enhancing plant defences and promoting resource efficiency, these approaches provide an essential foundation for resilient and environmentally responsible farming. Together, they highlight the need for a systems-level and interdisciplinary framework. Furthermore, the review emphasizes the critical role of sustainable agricultural practices, such as integrated pest management (IPM) and precision agriculture. These approaches reduce reliance on chemical inputs while bolstering a plant's natural defences. The review concludes that a multifaceted, interdisciplinary approach is essential for developing agricultural systems that can withstand the compounding pressures of climate change and a growing global population. By integrating advances in molecular breeding, beneficial microorganisms, and sustainable farming methods, we can enhance crop resilience and ensure a more stable and secure food supply for the future.