EXPLORING THE EFFECT OF Actinidia deliciosa EXTRACT FOR SKIN REVITALIZATION
SADIA RAFIQUE *
Faculty of Pharmacy and Alternative Medicine, The Islamia University of Bahawalpur, Punjab, Pakistan.
KANWAL IRSHAD
Department of Pharmaceutical Chemistry, Government College University, Faisalabad, Pakistan.
NADIA AFSHEEN
Department of Biochemistry, Riphah International University, Faisalabad, Pakistan.
ROMANA RIAZ
Department of Pharmaceutics, Bakhtawar Amin College of Pharmaceutical Sciences, Multan, Pakistan.
SIDRA MEER
Department of Pharmaceutical Science, The University of Faisalabad, Pakistan.
RIZWANA KAUSAR
ILM College of Pharmaceutical Sciences, Pakistan.
MUHAMMAD SHERAZ QURESHI
Bakhtawar Amin College of Pharmaceutical Sciences, Multan, Pakistan.
MUHAMMAD ISHFAQ KHAN
Department of Botany and Weed Science, The University of Agriculture Peshawar, Pakistan.
*Author to whom correspondence should be addressed.
Abstract
Background: The research project was designed to prepare the emulgel (O/W) from extract of Actinidia deliciosa to evaluate its effects on the skin of human.
Aim: To evaluate emulgels as a base prepared from fruit Actinidia deliciosa which was expected to reduce the erythema, melanin and sebum level of skin as well as to increase the moisture content in the skin and increase elasticity.
Methods: The emulgels (O/W) prepared from Actinidia deliciosa fruit extract. The prepared formulation contained 5% extract and base (extract exclude) were applied for the period of 3 months on the cheeks of 13 healthy female volunteer. The melanin, erythema, elasticity, moisture contents and sebum of skin were measured at baseline and then evaluate the effect of prepared formulation after every 14 days during the whole experimental period.
Results: The results obtained from formulation gel against base gel for skin melanin, erythema, sebum, elasticity and moisture contents showed the significant effect.
Conclusions: The prepared formulation was declared to be suitable anti-wrinkle, anti-aging, skin whitening agent and used for the treatment of many different dermatological preparations such as acne.
Keywords: Actinidia deliciosa, melanin, emulgels, elasticity, erythema, avocado fruit