RESPONSE OF DRUG AMALGAMATION THROUGH COPPER NANOPARTICLES AS MAJESTIC HELPERS TO HALT THE THIRD WAVE OF SARS-COV-2, A REVIEW
ASMA NAEEM
Department of Zoology, University of Punjab, Pakistan
FAIQA SHAHEEN
Faculty of Basic Sciences and Mathematics, School of Chemistry, Minhaj University Lahore, Pakistan.
ANILA SHAHZADI
Department of Zoology, University of Central Punjab, Pakistan
HAFIZ MUHAMMAD ARSALAN
Faculty of General Medicine, Altamimi Medical University, Bishkek, Kyrgyzstan
NAILA SARWAR
Faculty of Medicine and Allied Health Sciences, Islamia University Bahawalpur, Pakistan.
UME HABIBA
Faculty of Medicine and Allied Health Sciences, Islamia University Bahawalpur, Pakistan
NEELAM FARHEEN
Department of Biochemistry, Faculty of Health Sciences, Green International University, Lahore, Pakistan
HEWAD HEWADMAL
Department of Cardiology, Sheikh Zayed Medical College and Hospital, Rahim Yar Khan, Pakistan
SHAFIA ARSHAD *
Faculty of Medicine and Allied Health Sciences, Islamia University Bahawalpur, Pakistan
AMINA ARIF
Department of Biochemistry, University of Central Punjab, Pakistan.
*Author to whom correspondence should be addressed.
Abstract
The contemporary contagious ailment is caused by one of the deadliest coronaviruses, the SARS-COV-2. This novel zoonotic entity leads to multi-organ failure and an escalating threat and turbulence all over the world. Albeit a lot of work has been done to beat this virus, it is still radiating consistently. A colossal number of antiviral drugs has been tested to overcome the current pandemic but no promising remedy. A new approach to employ drug amalgamation such as remdesivir with hydroxychloroquine and losartan would better eradicate this outbreak. For this purpose, copper nanoparticles (extracted from a Prophetic, miraculous herb Nigella sativa) would serve as excellent transporters of such kinds of drug composites. In this review, the several possible therapies available across the world will be discussed in addition to the existing evidence for each of them. This new insight would be beneficial to fight against the latest rife.
Keywords: HCQ, losartan, remdesivir, copper nanoparticles, drug amalgamations, N. sativa