PHYTOCHEMICAL AND ANTHELMINTIC ACTIVITY INVESTIGATIONS EXTRACT OF Mimosa pudica Linn. ROOT EXTRACT
S. RAMESH *
Department of Botany, Khadir Mohideen College, Adirampattinam - 614 701, Thanjavur - Dt, Tamil Nadu, India.
G. VENKATESAN
Department of Botany, M. R. Government Arts College, Mannargudi – 614001, Thiruvarur - Dt, Tamil Nadu, India.
K. KARTHIKEYAN
Department of Botany, Government Arts College, Kumbakonam - 612 001, Thanjavur - Dt, Tamil Nadu, India.
C. CHANDRAN
Department of Botany and Microbiology, A.V.V. M Sri Pushpam College, Poondi - 613 503, Thanjavur - Dt, Tamil Nadu, India.
*Author to whom correspondence should be addressed.
Abstract
Mimosa pudica L. is commonly called sensitive plant it’s belongs to the family of Mimosaceae. The whole plant was highly medicinal properties and important used in several preparations of ayurvedic medicine. It has been reported that the phytochemical compounds revealed the presence of most highly in toxic alkaloids as mimosine and orientin, isoorientin, D-pinitol, norepinephrine mucilage, tannins, non-protein amino acid, tannins, flavonoids, C glycosides, steroids, terpenoids, fatty acids, saponins, coumarin, are also present. The anthelmintic activity of root was studied on adult Indian earthworm. Pheretima posthuma in 3-5 cm in length and 0.1-2 cm in width were used due to its anatomical and physiological resemblance with the intestinal roundworm parasite of human beings. The anthelmintic assay was carried out as per the method of Nargud with minor modification. 100 mg/ml, 200 mg/ml and 500 mg/ml dilutions of petroleum ether, ethanol and aqueous extract were prepared. Normal saline and albendazole served as control.
Keywords: Mimosa pudica, phytochemical, anthelmintic activity, medicinal uses, Pheretima posthuma