PLANT CELL BIOTECHNOLOGY AND MOLECULAR BIOLOGY

Introduction: The radiographic features that help the radiologist to make the diagnosis of a bone tumour or tumour-like lesion or narrow the diagnostic possibilities, include internal characteristics of the lesions, patterns of bone destruction, lesion margins,  location, site and position of the lesion in the skeletal system and in the individual bone and single or multiple lesion nature. These radiographic features with clinical information help to define whether the lesion is neoplastic or non-neoplastic, primary or metastatic.

Background: A systematic approach was useful for recognizing tumors of the spine with characteristic features such as Bone Island, osteoid osteoma, osteochondroma, chondrosarcoma, vertebral angioma, and aneurysmal bone cyst. In the remaining cases, the differential diagnosis included other primary spinal tumours, vertebral metastases and major non-tumoral lesions simulating a vertebral tumour, Paget disease, spondylitis, echinococcal infection and aseptic osteitis. In many cases, vertebral biopsy was warranted to guide treatment.

Objective: To correlate Magnetic resonance imaging findings with Radiograph findings and histopathological findings.

Result: Out of 44 cases of primary bone tumours, Giant cell tumour was most common pathology, observed in 9 cases followed by osteochondroma observed in 5 cases and by osteoid osteoma.

Conclusion: Lesions were more common in males than in females.