A RETROSPECTIVE STUDY ON PHARMACOLOGICAL ACTIVITIES OF Calatropis procera LINN
. AISHWARYA
School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab -144411, India.
VIJAY CHOPRA
School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab -144411, India.
AMRITPAL SINGH
School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab -144411, India.
MANISH VYAS
School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab -144411, India.
NAVNEET KHURANA
School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab -144411, India.
NEHA SHARMA
School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab -144411, India.
ROHIT THAKKAR *
School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab -144411, India.
HARMINDER SINGH
School of Chemical Engineering and Physical Sciences, Lovely Professional University, Phagwara, Punjab-144411, India.
NITIN TANDON
School of Chemical Engineering and Physical Sciences, Lovely Professional University, Phagwara, Punjab-144411, India.
PRAMOD YADAV
Department of Rasashastra and Bhaishajya Kalpana, All India Institute of Ayurveda, New Delhi-110076, India.
P. K. PRAJAPATI
Department of Rasashastra and Bhaishajya Kalpana, All India Institute of Ayurveda, New Delhi-110076, India.
MANISH GUPTA
Mittal School of Buisness, Lovely Professional University, Phagwara, Punjab -144411, India.
*Author to whom correspondence should be addressed.
Abstract
Plants and herbs are being used for the treatment of various diseases since ancient time due to their efficacy and availability. According to the World Health Organization, 80 % world population use herbs or medicinal plants in one or the other way as vegetables, spices, and medicines. These drugs can be used internally and externally to treat various disorders, which are also reported in recent studies. However, there is a need to explore their therapeutic potential by conducting pre-clinical and clinical studies. Numerous plants have been used in human life for various purposes, one such plant is Calatropis procera (C. procera). It has been used since ancient times and also reported to have multidimensional therapeutic activities in Ayurvedic, Arabic, and Unani medicine system. It consists of a variety of chemical constituents including stigmasterol, β-sitosterol, flavonoids, polyphenols, calotropin, calotropagenin, and calotoxin. Recent studies suggest its role in the management of bronchitis, baldness, hair loss, asthma, leprosy, intermittent fevers, eczema, elephantiasis, vertigo, toothache, and inflammation of rheumatoid arthritis. The present review explores its different pharmacological activities and therapeutic potential as well as its chemical compounds, geographical sources.
Keywords: Calatropis procera, pharmacological activities, polyphenols, anti-tumour.