Beta vulgaris (BEETROOT) DERIVED PHYTOCHEMICALS AGAINST SPHONGOMYELIN PHOSPHODIESTERASE OF Leptospira interrogans CAUSING JAUNDICE
SMRUTI RANJAN BEHERA
Centurion University of Technology and Management, Odisha, India.
UPENDRA KUMAR NAYAK
Centurion University of Technology and Management, Odisha, India.
SURAJ KUMAR SAHU
Centurion University of Technology and Management, Odisha, India.
AKSHAYA KUMAR SAHOO
Centurion University of Technology and Management, Odisha, India.
PRASIDADITYA MOHANTY
Centurion University of Technology and Management, Odisha, India.
RAJASHREE MISHRA
Centurion University of Technology and Management, Odisha, India.
MUKUNDJEE PANDEY *
Centurion University of Technology and Management, Odisha, India.
*Author to whom correspondence should be addressed.
Abstract
Phytochemicals from Beet root plant extract can cure Jaundice. It is caused by Leptospira interrogans. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that caffeice acid and myricetin can effectively deactivate the sphongomyelin phosphodiesterase enzyme thereby interrupting the life cycle of the organism.
Keywords: Phytochemical, Beta vulgaris, Leptospira interrogans