Nigella sativa DERIVED PHYTOCHEMICALS AGAINST SHIKIMATE DEHYDROGENASE OF Staphylococcus aureus CAUSING ECZEMA
DIPTIPRAJNYA SAHOO
Centurion University of Technology and Management, Odisha, India.
MINATI NAYAK
Centurion University of Technology and Management, Odisha, India.
SARTHAK SIDDHANT MISHRA
Centurion University of Technology and Management, Odisha, India.
DIPANKAR BHATTACHARYAY
Centurion University of Technology and Management, Odisha, India.
MUKUNDJEE PANDEY *
Centurion University of Technology and Management, Odisha, India.
*Author to whom correspondence should be addressed.
Abstract
Phytochemicals from Nigella sativa plant extract can cure Eczema. It is caused by Staphylococcus aureus. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that Carvacrol can effectively deactivate the shikimate dehydrogenase enzyme thereby interrupting the life cycle of the organism.
Keywords: Phytochemical, Nigella sativa, Staphylococcus aureus.