KEWDA FLOWER DERIVED PHYTOCHEMICALS AGAINST Helicobacter pylori CAUSING ULCER
PRATYASA PRADHAN
Centurion University of Technology and Management, Odisha, India.
NIBEDITA PATRA
Centurion University of Technology and Management, Odisha, India.
JOGESH KUMAR NAYAK
Centurion University of Technology and Management, Odisha, India.
SOUMYA JAL
Centurion University of Technology and Management, Odisha, India.
DIPANKAR BHATTACHARYAY *
Centurion University of Technology and Management, Odisha, India and Go to Market Laboratory, Gram Tarang, Odisha, India.
*Author to whom correspondence should be addressed.
Abstract
Phytochemicals from Kewda flower (Pandanus odorifer) extract is traditionally employed for curing ulcer. The ulcer is caused by Helicobacter pylori. Biovia Discovery Studio was used to study the molecular docking of the phytochemicals with the enzyme. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that “Heptane and 1,2,3-benzene triol” can effectively deactivate the Sikhimate dehydrogenase enzyme thereby discontinuing the life cycle of Helicobacter pylori.
Keywords: Phytochemicals, Kewda flower, Helicobacter pylori.