Celastrus paniculatus DERIVED PHYTOCHEMICALS AGAINST SKIN DISEASE
BIDYASHREE TRIPATHY
Centurion University of Technology and Management, Odisha, India.
SIDHARTHA RAY
Centurion University of Technology and Management, Odisha, India.
JOGESH KUMAR NAYAK
Centurion University of Technology and Management, Odisha, India.
SOUMYA JAL
Centurion University of Technology and Management, Odisha, India.
DIPANKAR BHATTACHARYAY *
Centurion University of Technology and Management, Odisha, India and Go to Market Laboratory, Gram Tarang, Odisha, India.
*Author to whom correspondence should be addressed.
Abstract
Phytochemicals from that Celastrus paniculatus plant extract can be used to cure skin diseases. It is caused by Staphylococcus aureus. “Molecular docking method” of the phytochemicals with the enzyme was studied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that the phytochemicals alkaloids, stearic acid, betacyperonethe (benzene), and polyalcohol (ethanol) can effectively deactivate the L-lactate dehydrogenase enzyme thereby interrupting the life cycle of Staphylococcus aureus.
Keywords: Phytochemical, Celastrus paniculatus, Staphylococcus aureus.