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Phytochemicals are non-nutritive compounds obtained from plants. It has been reported that Coriandrum sativum plant extract is used to cure tooth cavity. The plant extract contains different phytochemicals. Tooth cavity is caused by Lactobacillus casei. One of the key enzymes involved in its biochemical pathway is cyclopropane-fatty-acyl-phospholipid synthase. The molecular docking of the phytochemicals with the enzyme was studied using Biovia Discovery Studio. The strength of the interaction was evaluated based on -CDocker energy and -CDocker interaction energy. High positive values for both the parameters indicated that out of different phytochemicals petroselinic acid can effectively deactivate the cyclopropane-fatty-acyl-phospholipid synthase enzyme thereby interrupting the life cycle of Lactobacillus.
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