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A cross sectional study was carried out in the fertility clinic of the Gampaha Wickramarachchi Ayurveda Hospital in Sri Lanka (August 2014 to May 2017) to screen the seminal parameter which is most liable to be affected in the males with fertility issues. The male infertility is increasing in the modern society. The poor quality semen can cause to male infertility. The quality of semen is decided by four main seminal parameters naming semen volume, sperm count, sperm motility and morphology. Thus, the defective seminal parameters lead to poor quality semen hence male infertility. Most of the causes for defective seminal parameters are unknown. Due to the fact that the male fertility is increasing day by day, it is important to find out the seminal parameter which is most liable to be subnormal/defective for the treating purposes of male infertility. The study which was carried out with 100 males with fertility issues disclosed that the seminal volume is the most liable seminal parameter which is to be affected easily. Thus, under the outcome of the study, it is better to pay the attention on seminal volume in the event of treating male infertility.