ANTIBACTERIAL ACTIVITY OF Zingiber officinale RHIZOME EXTRACT AGAINST CLINICAL Staphylococcus aureus

Main Article Content

S. A. ADEGOKE
S. MEPAIYEDA
K. BELLO

Abstract

Ginger (Zingiber officinale) has long been used as naturopathy due to their potential antimicrobial activity against different microbial pathogens. Moreover, in many countries like Nigeria, ginger is used in combinations as food recipes. This study was conducted to determine the antimicrobial activity of ginger extract, using disc agar diffusion method, the antibacterial properties of ginger rhizome extract was screened on Staphylococcus aureus The present study showed the potent antimicrobial activity of the ginger extract against Staphylococcus aureus with the highest zone of inhibition (17.0 mm) at 200 mg/ml and the lowest zone of inhibition (0.0 mm) at 1.8 mg/ml. The Minimum Inhibitory Concentration and Minimum Bactericidal Concentration of the ginger extract were 125 mg/ml and 175 mg/ml respectively. There was no statistically significant difference to the zone of inhibition of the extract as the concentration increases at P0.05. Ginger extract has high antibacterial properties at low concentration and therefore could serve as an alternative towards tackling the menace of Methicillin and Vancomycin-resistant strain of Staphylococcus aureus.

Keywords:
Antibacterial, bacteria resistance, ginger, nosocomial infection, Staphylococcus aureus.

Article Details

How to Cite
ADEGOKE, S. A., MEPAIYEDA, S., & BELLO, K. (2019). ANTIBACTERIAL ACTIVITY OF Zingiber officinale RHIZOME EXTRACT AGAINST CLINICAL Staphylococcus aureus. Journal of Biology and Nature, 10(1), 34-37. Retrieved from http://www.ikprress.org/index.php/JOBAN/article/view/4772
Section
Original Research Article

References

Sharma S, Vijayvergia R, Singh T. Evaluation of antimicrobial efficacy of some medicinal plants. J. Chem. Pharm. Res. 2010;2(1):121-124.

Weiss EA. Essential Oil Crops, CAB International, Oxon, UK & New York. 1997;76.

Kuschener WG, Stark P. Occupational toxicants exposure has an important role in many cases of lung diseases seen in workers. Occupational lungs diseases. Part 1. identifying work. Related asthma and other disorders. Postgrad. Med. 2003;113(4):70-78.

McGee H. On food and cooking. The science and lore of the kitchen.2nd Edition. Harold McGee (Ed). New York. 2004;425-426.

Chesbrough M. District laboratory practice in tropical countries. Part II. Cambridge Low price Education. 2002;132 – 142.

O’Hara M, Keifer D, Farrel K, Kemper K. A review of 12 commonly used medicinal herbs. Archives. Fam. Med. 1998; (7):523-536.

Pankaj Sah, Al-Tamimi B, Al-Nassri N and Al-Mamari R. Effect of temperature Reichb. (Rutaceae). Afr. J. Biotechnol. 2012;8(22): 6346-6348.

Khulbe K, Sati SC. Antibacterial Activity of Boenninghausenia albiflora on antibiotic properties of garlic (Allium sativum L.) and ginger (Zingiber officinale Rosc.). African Journal of Biotechnology. 2009;11(95):16192-16195.

Ernst E, Pittle MH. Efficacy of ginger for nausea and vomiting systematic review of randomized clinical trials. British Journal of Anesthesia. 2002;84(3):367-371.