Journal of International Research in Medical and Pharmaceutical Sciences

The antibacterial activity of Tetmosol^R, Dudu Osun^R, Dettol^R, Life Buoy^R and Tura^R were evaluated against Stapylococcus aureus, Pseudomonas specie, Salmonella typhi, Klebsiella specie, Streptococcus specie and Proteus vulgaris obtained from infected wounds of patients from Delta State University health centre Abraka. The antimicrobial activity of various dilutions of the soap samples was evaluated by the Agar Diffusion. From the results obtained, Dudu Osun^R and Life Buoy had the highest Zone of Inhibition (19 mm) at 10 mg/ml Least Zone of Inhibition was recorded for all Antiseptic soap at 100 mg/ml. Tetmosol was the most effective among the soaps and Dettol^R was the least effective while Pseudomonas specie was the most resistant pathogenic organism. In order of effectiveness, the performances of the soaps were; Dudu Osun^R and Tetmosol^R 23% > life Buoy^R 22% > Tura^R 20%> Dettol^R 12% For MIC, all the antiseptic soaps had no MIC for Pseudomonas species; Dudu Osun^R had MIC of 0.01mg/ml for Staphylococcus species and 10 mg/ml for the other test organisms; Dettol^R had MIC of 1mg/ml; Tura^R, Life buoy^R and Tetmosol^R had MIC of 10 mg/ml. For antibiotic susceptibility testing in the order of % antibiotic Sensitivity Proteus and Klebsiella (80%)>Streptococcus species (73.3%)>Staphylococcus aureus and Salmonella typhi (66.7%)>Pseudomonas species (46.7%). A total of 33.3% of all test organisms were sensitive to (Perfloxacin, Ciprofloxacin, Streptomycin, Septrin, and Tarivid)  antibiotics. In the order of % antibiotic resistance, Pseudomonas species 53.3%>Salmonella typhi, Staphylococcus aureus and Streptococcus species 33.3%>Proteus vulgaris and Klesiella species (20%). A total of 20% of all test organisms were resistant to (Ampiclox, Zinnacef,and Amoxicillin) antibiotics.