CHEMICAL AND MINERALOGICAL CHARACTERIZATION AND ANTI-INFLAMMATORY ACTIVITY EVALUATION OF SENEGAL’S MUDS

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ROKHAYA SYLLA GUEYE
AWA NDIAYE SY
INSA BADIANE
MOUHAMADOU BASSIR DIOP
CHEIKH SALL
MAMADOU BALDE
MADIEYE SENE
YOUSSOU NDAO
ADAMA DIEDHIOU
GUATA YORO SY
MATAR SECK
DJIBRIL FALL
ALASSANE WELE

Abstract

Clays have been use in therapeutics for a long time and proliferation of thermal mud centers testifies to its effectiveness. In our work, anti-inflammatory activity of Ziguinchor mangrove sludge and Mbodiène attapulgite was evaluated, after a chemical and mineralogical characterization. Results obtained showed for mangrove mud multiple components with mainly varying contents in sodium, aluminum, chlorine, silicon and iron. Attapulgite was predominantly composed of silicon 55.15%, magnesium 13.8%, calcium 11.11%, iron 8.3% and aluminum 7.78%. The cation exchange capacity evaluated with the cobaltihexamine ion was 95 meq / 100 g for Attapulgite versus 6.85 meq / 100 g for the mangrove mud. Mineralogical analysis has shown that mangrove mud consists essentially of kaolinite and palygorskite is the dominant mineral of attapulgite with quartz, crystals of ankerites, dolomites. Anti-inflammatory activity evaluation showed a percentage of inhibition of edema induced in croton oil from 25.23% for attapulgite, to 28.34% for Ziguinchor mud, against 52, 26% for Voltaren Emulgel® as reference. These results predict a good way of additional treatment at lower cost for pathologies such as osteoarthritis.

Keywords:
Clays, mudflat, attapulgite, antiinflammatory activity

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How to Cite
GUEYE, R., SY, A., BADIANE, I., DIOP, M., SALL, C., BALDE, M., SENE, M., NDAO, Y., DIEDHIOU, A., SY, G., SECK, M., FALL, D., & WELE, A. (2017). CHEMICAL AND MINERALOGICAL CHARACTERIZATION AND ANTI-INFLAMMATORY ACTIVITY EVALUATION OF SENEGAL’S MUDS. Journal of Applied Chemical Science International, 8(3), 95-105. Retrieved from http://www.ikprress.org/index.php/JACSI/article/view/3819
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Original Research Article